FerriScan for Clinicians

Why Choose FerriScan

FerriScan provides an accurate measurement of liver iron concentration (LIC) through a non-invasive, MRI-based technology. FerriScan was regulatory cleared by the FDA for the measurement of LIC in 2005. In January 2013 FerriScan gained an additional clearance from the FDA as a companion diagnostic to aid in the identification and monitoring of non-transfusion-dependent thalassemia patients receiving therapy with deferasirox. FerriScan is now internationally recongized as the gold standard in liver iron concentration (LIC) measurement.

FerriScan has originally been validated against liver biopsy on several makes and models of MR scanner in hundreds of patients, and has high sensitivity and specificity for measuring LIC. FerriScan results are clinically validated to be unaffected by inflammation, fibrosis or cirrhosis. To date, FerriScan has been used for over 50,000 patient measurements at hundreds of MR centers worldwide. FerriScan has also now been used in many multi-national, multi-site clinical trials by pharmaceutical companies.

Advantages of FerriScan over serum ferritin (SF)

Advantages of FerriScan over liver biopsy

Advantages of FerriScan over Liver T2* (MRI)

Comparison of Studies Conducted Using FerriScan and T2* MRI

Range of LIC Results Produced by Different T2* Calibrations

FerriScan Reimbursement


FerriScan is reimbursed in all Canadian provinces as an ‘Out-of-Country Medical Service’. The treating clinician must forward an application for each patient to the province’s Ministry of Health (MOH) for approval. Once approved, the MOH will grant a timeframe for the patient to have their FerriScan and/or Cardiac T2*. 

To help with the application process, we’ve compiled a list of resources that may help you with your prior approval submissions:

British Columbia
Nova Scotia

Generally, in-patients receive full reimbursement for FerriScan and have no out-of-pocket expenses.


FerriScan is reimbursed at public hospitals through the local NHS Trust system.


FerriScan has been used in the United States since 2005, when FDA clearance for FerriScan was obtained. Since that time, over 13,000 FerriScans have been performed for US patients at a number of US hospitals and radiology facilities.

The cost of the MRI scan (or part of the cost) is usually covered by insurance companies (payers). Pre-authorisation is recommended, as is common for MRI testing. However, the cost associated with the FerriScan image analysis may not be covered, resulting in the hospital or patient having to cover this cost, together with any co-pay associated with the imaging.

FerriScan has now been deemed eligible for reimbursement by some US Insurance Companies:

  • Health Net. Prior authorization is required to confirm the medical necessity of a FerriScan
  • Kaiser Permanente SE Atlanta. Prior authorization is required to confirm the medical necessity of a FerriScan
  • Medical Mutual of Ohio. No prior authorization is required

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